Evidence table for systematic reviews
Study reference Design Inclusion Criteria Quality Results Comments

Baker, 2009

Cochrane systematic review of (quasi-) randomised studies

Inclusion criteria:
Randomised or quasi-randomised studies that assessed one or more types of psychological or non-psychological interventions for the treatment of non-epileptic seizures (NES)

 

Exclusion criteria:
Studies of childhood NES

 

 

Search: adequate

 

Selection: adequate

 

Quality assessment of individual studies: adequate

Moene 2002 (therapy programme & hypnosis vs therapy programme)

Results:
No significant condition effects 

 

Limitations: small study population (n=45) of which only 8 were reported to have seizures or convulsions and 7 were reported to have parocysmal myoclonic outbursts. No further details were given for (change in) seizure frequency, quality of life or seizure severity

 

 

Moene 2003 (hypnosis vs control/ waiting list)


Results: significant treatment results for a hypnosis-based treatment in patients with a conversion disorder, motor type in VRMC (Video Rating Scale for Motor Conversion Symptoms) scores and on the measure of general motor impairment of the ICIDH (International Classification of Impairments, Disabilities and Handicapts) (6 months after 10th session) p=0.001 and <0.01

 

Limitations: small study (n=44) of which only 2were reported to have seizures or convulsions and 6 were reported to have parocysmal myoclonic outbursts. No further detals were given for (change in) seizure frequency, quality of life or seizure severity

 

Ataoglu 2003 (paradoxical intervention vs diazepam as outpatient

 

Results: percentage of sample in group who showed no conversions symptoms (attacks) in the last two weeks at follow up:

I: 14/15 (93.3%)

C: 9/15 (60%)

P= 0.034

Greater degree of significance was found in the I-group when comparing the difference between pre- and post-treatment anxiety scores

 

Limitations: no specific attack frequency or severity results, small study (n=15), no discussion of medication use, absence of a placebo control group and different settings between groups (inpatient - outpatient)